Introduction to Air Conditioning VHP Sterilization System

The Teling Biological Air Conditioning System VHP Sterilization System adopts the most advanced VHP sterilization technology currently available, providing domestic users with the most reliable, universal, and customized VHP sterilization system. Through continuous research and development, we constantly update our products and technologies, and apply new technologies to our air conditioning VHP sterilization system, benefiting our customers.

Our products have been selected by many of the most well-known biopharmaceutical companies, laboratories, research institutions, universities, and government departments in China. The product quality of the Teling Biotech brand and the dedication of its employees have contributed to today's success, and we will never stop pursuing excellence.
We not only provide standard VHP sterilization equipment, but also offer customized designs, rich options, and supporting services to meet international certification requirements such as FDA, EU, and WHO.
Supporting options: audit trail; Electronic signature; Electronic records (PDF reports); Remote control options, etc.
Supporting services: installation and debugging services, IQ/OQ/PQ verification services, preventive maintenance, and spare parts supply.
1. Low operating costs: Our product has no special components, and all spare parts can be purchased in the market;
2. Rich options for customized production: We have standardized the types and options of VHP sterilizers, providing customers with a wide range of choices according to their needs, as well as customized production based on their actual situation to meet their sterilization needs;
3. Real time monitoring and data storage: It can achieve device data storage, sterilization cycle reminder and abnormal alarm, as well as real-time monitoring of equipment;
4. Easy to use: Adopting a user-friendly and user-friendly interface design, even for personnel who have not used it before, they can operate and use it without barriers after simple training;
5. Dry process assurance: The Teling Biological VHP sterilizer ensures that the VHP in the entire sterilization process does not condense from the generation, disinfection, and degradation stages through process saturation control and dew point monitoring, ensuring the vaporization state of the entire process.

The Teling Biological VHP generator uses low-temperature flash evaporation to achieve vaporization of high concentration hydrogen peroxide, and the generator adopts standardized modules. The equipment adopts a stainless steel structure as a whole, and can be configured according to different customer needs to meet high standard usage requirements such as clinical, life science, pharmaceutical, P3 biosafety laboratory, etc.
The TransBio VHP sterilization system uses a linkage with the air conditioning system to achieve sterilization. Each device has 20 editable programs and can be linked to up to 20 air conditioning units.
As shown in the figure, each device adopts 4-6 sets of standard generation modules, 2 sets of parallel rotary dehumidification systems, EDPM sealed butterfly valves for valves, and BMS system linkage control. The conveying pipeline adopts anti-corrosion (galvanized layer thickness ≥ 120g/㎡) air ducts. Due to the long pipeline transportation, the insulation effect of the conveying pipeline is required to be high. The pre insulation pipeline has a heat resistance coefficient R value greater than 1.2, ensuring that the entire conveying pipeline will not be affected by external environmental temperature and humidity, and will not condense during the transportation process.
The BMS system of the air conditioning system is linked with the VHP main control system. The air conditioning system needs to set a disinfection mode, and the air conditioning needs to be frequency reduced during the disinfection mode. The air conditioning supply adopts a low circulation scheme to change the gas flow pattern of the clean room, so that the clean room air is in a turbulent state, thereby achieving uniform distribution of VHP. After entering the disinfection mode, the BMS sends a disinfection command to the VHP sterilization system, and the VHP system enters a disinfection enabled state, at which point the corresponding unit's sterilization program is initiated.

The VHP conveying pipeline adopts pre insulated pipelines, which are insulated, corrosion-resistant, and fire-resistant, suitable for long-distance hydrogen peroxide pipeline transportation. As shown in the figure below, pre insulated pipelines can be made into various shapes of conveying pipelines, which are convenient, durable, and corrosion-resistant.
When conducting VHP pipeline transportation, attention should be paid to the connection method and position between the VHP transportation pipeline and the main air supply pipe. Due to the galvanized material on the inner wall of the air conditioning duct, it will accelerate the degradation of hydrogen peroxide. Therefore, it is necessary to minimize the distance between the pipeline before high concentration VHP enters the sterilization area room. The input position should be at the end of the main air supply pipe. The connection method between the VHP transportation pipeline and the main air supply pipe is shown in the following figure, and the sealing of the connection should be considered.

For the case where multiple HVAC systems share a VHP sterilization system, it is necessary to comprehensively consider the position of each system, ensure that the total length of each conveying pipeline does not exceed 100 meters, and minimize the number of bends.
The schematic diagram of VHP sterilization scheme for air conditioning system is as follows

Air conditioning room in a pharmaceutical factory
The validation of VHP sterilization effect is carried out in the following four stages: parameter development, VHP distribution, biological challenge experiment, and exhaust research stage.

The document system and verification execution are strictly carried out in accordance with the V-Model method, providing a bilingual verification document system in both Chinese and English to meet the requirements of FDA and EU GMP. Currently, there are abundant cases of foreign certified customers and biopharmaceutical customers, and the document system is carried out according to the following model:

The public engineering system requires the cooperation of Party A. The Teleon VHP sterilization system requires a 380V/50Hz power supply, with a maximum operating power of 15KW. A compressed air source is required for valve control, with a compressed air pressure requirement of 6-8 kilograms.
The control of the TransBio VHP sterilization system is entirely based on Siemens PLC control. Products with GMP requirements use a 12.1-inch industrial computer control screen, with multiple application programs available, such as LOGA sterilization program, LOGB concentration sterilization, etc. User permission management is set up, the system comes with audit tracking, electronic signature function, and data and charts can form PDF reports to meet GMP requirements.
The operation interface is clear and concise, the safety parameter control is reasonable, the upper and lower limits of process saturation are set, and the program is stable:

The core components of the equipment are all from major brands, such as German EBM fans for fans, and imported brands for fans with cleanliness and anti-corrosion requirements.
The control sensors are all selected from brands and models that have been tested for a long time, such as the VHP concentration sensor and temperature and humidity sensor, which are selected from the Finnish VAISALA HPP272 model